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Specific disruption of calcineurin-signaling in the distal convoluted tubule impacts the transcriptome and proteome, and causes hypomagnesemia and metabolic acidosis
Banki E, Fisi V, Moser S, Wengi A, Carrel M, Loffing-Cueni D, Penton D, Kratschmar DV, Rizzo L, Lienkamp S, Odermatt A, Rinschen MM, Loffing
Kidney Int. 100(4):850-869. (2021)
https://doi.org/10.1016/j.kint.2021.06.030
Collecting system-specific deletion of Kcnj10 predisposes for thiazide- and low-potassium diet-induced hypokalemia
Penton D, Vohra T, Banki E, Wengi A, Weigert M, Forst AL, Bandulik S, Warth R, Loffing J
Kidney Int. 97(6):1208-1218 (2020)
https://doi.org/10.1016/j.kint.2019.12.016
Protein Phosphatase 1 Inhibitor-1 Mediates the cAMP-Dependent Stimulation of the Renal NaCl Cotransporter
Penton D, Moser S, Wengi A, Czogalla J, Rosenbaek LL, Rigendinger F, Faresse N, Martins JR, Fenton RA, Loffing-Cueni D, Loffing J
J Am Soc Nephrol. 30(5):737-750 (2019)
https://pubmed.ncbi.nlm.nih.gov/30902838/
Mechanisms of renal control of potassium homeostasis in complete aldosterone deficiency
Todkar A, Picard N, Loffing-Cueni D, Sorensen MV, Mihailova M, Nesterov V, Makhanova N, Korbmacher C, Wagner CA, Loffing J
J Am Soc Nephrol. 26(2):425-38 (2015)
https://pubmed.ncbi.nlm.nih.gov/25071088/
Protein phosphatase 1 inhibitor-1 deficiency reduces phosphorylation of renal NaCl cotransporter and causes arterial hypotension
Picard N, Trompf K, Yang CL, Miller RL, Carrel M, Loffing-Cueni D, Fenton RA, Ellison DH, Loffing J
J Am Soc Nephrol. 25(3):511-22 (2014)
https://pubmed.ncbi.nlm.nih.gov/24231659/
Rapid dephosphorylation of the renal sodium chloride cotransporter in response to oral potassium intake in mice
Sorensen MV, Grossmann S, Roesinger M, Gresko N, Todkar AP, Barmettler G, Ziegler U, Odermatt A, Loffing-Cueni D, Loffing J
Kidney Int. 83(5):811-24 (2013)
https://doi.org/10.1038/ki.2013.14